It's a good idea to clean artwork once every two weeks, as dirt makes the surfaces of artwork look dull and can cause deterioration. To be safe, handle artwork while wearing cloth gloves to avoid getting fingerprints or dirt on the surface of work. Do not apply
cleaning solutions, solvents, sprays, or insecticides near or directly to any work of art. Use canned air or a soft natural-bristle brush to clean sculptures and paintings.
For plexiglas frames, the surface should be cleaned with a plastic cleaner, not commercial glass cleaner. Use a non-abrasive cloth and first spray the plastic cleaner on the cloth before you clean the surface. Do not use paper towels because they will cause scratches and leave a residue on the surface.